The Food and Drug Administration says there is little evidence that testosterone-boosting drugs taken by millions of American men are advantageous, though the agency is, in addition, not convinced by studies implying the hormone carries serious risks. The group said it's especially significant for men who have had a heart attack, stroke or other heart-related event http://tinyurl.com/zwvtvex
in the previous six months to prevent testosterone therapy. On the other hand, testosterone therapy is safe and effective for the treatment of young men with hypogonadism (testosterone deficiency) that resulted from a disease of the testes, pituitary or hypothalamus. Having too much body fat affects your hormone balance of estrogen/ estradiol and testosterone.
We are also requiring manufacturers of authorized testosterone products to run a well-designed clinical trial to clearly address the question of whether an increased danger
of stroke or heart attack exists among users of these items. We encourage patients and health care professionals to report side effects including testosterone products to the FDA MedWatch
program, using the information in the Contact FDA" carton at the bottom of the page.
Men and women in the United States have used testosterone therapy in many instances, since the late 1930s for more than 40 years - with just rare adverse effects. The number of girls in America currently on testosterone treatment is estimated to be in the tens of thousands - miniscule compared with the millions prescribed oral estrogen-progestin regimens, like Provera and Premarin. With a growing recognition of the advantages of testosterone for women, those amounts http://tinyurl.com/zwvtvex
may grow, but it might still be some time before the treatment reaches the mainstream.
The Endocrine Society added that more large, randomized controlled studies are needed to investigate the dangers and benefits of the therapy for older guys. Meanwhile, the group suggested that middle-aged and older guys who are thinking about using testosterone therapy to treat age-associated decrease in this hormone should be warned about the possibility of heart-related side effects.